American Chemical Society: Analytical Chemistry Table of Contents

Crystal structure of an antipsychotic agent, 2-(4-ethyl-1-piperazinyl)-4-(4-fluorophenyl)-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine (blonanserin).

both dopamine D2 and serotonin 5-HT2 receptor antagonist properties.1 In the chemical structure, this compound is different from all of the currently known antipsychotics, such as haloperidol, chlorpromazine and risperidone.2 To understand the structure-activity relationships of antipsycotics, an X-ray analysis of the title compound was undertaken. A colorless platelet crystal was obtained from...

Crystal and molecular structure of (-)-17-hydroxy-neo-clerod-3-en-15-oic acid from Gymnosperma glutinosum.

structure elucidation of two new diterpenes from Gymnosperma glutinosum.1 The chemical structure of the neo-clerodane compound was established on the basis of 1H and 13C nmr spectroscopic studies and chemical reactions, but the stereochemistry at C-13 could not be determined. Therefore we carried out an X-ray crystal analysis of (–)-17-hydroxy-neoclerod-3-en-15-oic acid (Fig. 1) in order to obt...

American Chemical Society: Environmental Science & Technology Table of Contents

A near infrared spectroscopic discrimination of noodle flours using a principal-component analysis coupled with chemical information.

Using a portable near infrared (NIR) spectrometer, we discriminated flours for making Japanese noodles (Soba), not only relying on a statistical and mathematical approach, but also on a chemical interpretation of the NIR spectra. In original NIR spectra, the particle-size difference, which results in an undesired systematic variation, was extracted and interpreted as the first-principal compone...

Determination of the carbon, hydrogen and nitrogen contents of alanine and their uncertainties using the certified reference material L-alanine (NMIJ CRM 6011-a).

The carbon, hydrogen, and nitrogen (CHN) contents of alanine and their uncertainties were estimated using a CHN analyzer and the certified reference material (CRM) L-alanine. The CHN contents and their uncertainties, as measured using the single-point calibration method, were 40.36 ± 0.20% for C, 7.86 ± 0.13% for H, and 15.66 ± 0.09% for N; the results obtained using the bracket calibration met...